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Year : 2022  |  Volume : 7  |  Issue : 1  |  Page : 1-7

Clinico-pathological evaluation of breast cancer in a Nigerian tertiary care center

1 Department of Histopathology, Delta State University, Abraka, Delta State, Nigeria
2 Department of Surgery, Igbinedion University, Okada, Edo State, Nigeria

Correspondence Address:
Dr. Obiora Jude Uchendu
Department of Histopathology, Delta State University, Abraka, Delta State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmwa.jmwa_6_22

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BACKGROUND: Breast cancer (BC) is a major public health concern globally. In Nigeria, it is the most common cancer in females and is often diagnosed at an advanced stage as an aggressive disease. OBJECTIVE: The study hopes to assess the clinical and morphologic features of BC specimens in Delta State University Teaching Hospital DELSUTH, Nigeria. METHODS: This is a retrospective cross-sectional study at the Pathology department of a DELSUTH, from January 1, 2014 to March 30, 2020. The age, gender, laterality, histological diagnosis, tumor grade, and year of diagnosis of these BC were analyzed with Microsoft Excel spreadsheet 2007 and presented in tables and figures. RESULTS: The study comprised 237 BC patients, accounting for 35.5% of total cancer and consisting of 6 (2.5%) males and 231 (97.5%) females with a mean age of 48.21 years. The age group 30–59 years accounted for 80.2% of the cases. The annual incidence rose to a peak in 2019. Bilateral, right breast, and left breast cancer accounted for 6 (3%), 109 (46%), and 122 (51%) cases respectively. Most cases were invasive ductal carcinoma (IDC) (89.9%). Well-differentiate (12.2%), moderately differentiated (19.0%) and poorly differentiated (68.8%) cancer accounted for 12.2%, 19% and 68.8% of the cases respectively. CONCLUSION: BC constitutes a serious growing but poorly addressed health burden affecting mainly Nigerian young and middle-aged women. Most cases are IDC, and Grade III tumors. There is a need to address the gap in prevention, early diagnosis and quality management of BC in developing countries.

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